Amir Jaffer How many lives do you think could be saved with better compliance with VTE prophylaxis? What is the current rate of thromboembolic disease after major surgery in the developed world?

Andy Rhodes What type of patients are likely to derive the most benefit from monitored perioperative fluid therapy? Can an arterial line replace CVC and PAC in perioperative medicine?

Christoph Hofer What group of patients benefit from monitoring and manipulation of perioperative haemodynamics? How do I guide fluid therapy for a laparotomy? How often do you push patients to supranormal levels? Where do you think cardiac output monitoring will be in 15 years time?

Daniel Conway Do you believe that cardiac output monitroing for major surgery should be a standard of care? How big an influence do you think enhanced surgical recovery programs have been to the adoption of technology Why has it taken so long for Cardiac Output Monitoring to be adopted in perioperative care

David Hepner What is the risk of spinal or epidural haematoma with concurrent antiplatelet medication What guidelines do you use for managing the anticoagulation of your patients prior to neuraxial techniques

Giorgio Della-Rocca Do dynamic indices have any place in spontaneously breathing patients? Where do you see the future of pulse pressure analysis?

Greg McAnulty How does a protective strategy differ from that used in ITU? Should we be praticing lung protective ventilation for all surgical patients?

Hilary Grocott What is the likely pathophysiology underpinning perioperative cognitive change? Is it possible to predict those patients who are likely to have a reduction in cognitive function after surgery?

Howard Wakeling "Your study used a very simple approach through stroke volume maximisation, would you modify that approach if you did another study?" How do you categorise a moderate or high risk patient? Is it important to identify the high risk patient or is it time to optimise everybody?

Jochen Mayer What approach do you use to guide fluid therapy? What are the challaneges of bringing the results of an outcome study into clinica practice?

Lee Fleisher What have been the two biggest drivers for change on perioperative care quality in the last two years? is outpatient surgry risk free?

Mark Hamilton Have we proved beyond all doubt that optimisation works or do we need more studies? The evidence you presented is very strong. Why is haemodynamic optimisation not always used?

Monty Mythen What are the key components of a successful enahanced surgical recovery program? What are the advantages of an enhanced surgical recovery program? "is ESR or ""fast tracking"" a new standard of care or simply what we have been doing better?"

Nick Black Patients are surley the best judge of their outcome but how do you manage their expectations given the limited contact time health care professionsals have with their patients? "Are there any patient report systems comparable to PROMS, currently being used in the world to influence a change in care?"

Peter Lindenauer Should we broaden our measurements when looking at hospital outcome data? The surgical care improvement program has recently come under criticism for not improving outcome as planned - could you comment? The paper by Ghaeri et al in the NEJM last year suggests there is still a large variation in hospital mortality do you think transparency alone is likely to improve that?

Pierre Squara In which departments can less invasive monitoring be used now? Which new grounds can less invasive technologies allow us to explore?

Rafael Blanco Is it possible to teach yourself regional anesthesia? Is it clear that ultrasound guided regional anesthesia is safer than nerve stimulation techniques? Do regional anaesthesia courses influence training when delgates are back in their hospitals?

Ross Kerridge Fdifferent anaesthetists practice in different ways-how can you cater for this in a preoperative clinic? The evidence that perioperative assessment clinics make a significant diference to patient outcome is not robust-should we abandon clinics?

Vanya Gant What is the future for antibacterial substances? Is Surgical antibiotic prophylaxis truly effective? Is Surgical antibiotic prophylaxis truly effective?

Will Harrop-Griffiths Does the literature support the notion that an ultrasound guided approach is safer than nerve stimulation alone? The explosion of ultrasound guided regional anaesthesia has led to a new standard-do you agree?

Dr Andy Bodenham General versus Local Anaesthesia for Carotid Surgery

Dr Angela Bader Anaesthesia and neurological disease

Dr Ian Calder Recent advances in airway management

Dr Tim Cook NAP3 safety of neuraxial blockade

Professor Brian Cuthbertson Biomarkers and Assessment of Risk in Major Surgery

Professor W. Scott Beattie Randomised and Nonrandomised Evidence and the Aprotinin Story